World J Oncol

World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access

Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc

Journal website https://wjon.elmerpub.com

Original Article

Volume 000, Number 000, September 2026, pages 000-000

Socioeconomic Changes During Cancer Therapy and Their Associations With Functional Decline and Treatment Delivery: A Multicenter Prospective Study

↓ Figure 1. Study flowchart of participant recruitment and follow-up. T0: baseline assessment; T1: follow-up assessment.

↓ **Table 1.** Definition of T0 and T1 Changes
Variables	Definition
ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network.
Socioeconomic factors
Change in occupational status	Defined as a deterioration in occupational status between baseline (T0) and follow-up (T1). Participants were categorized as having occupational loss if they transitioned from employment at T0 to unemployment at T1.
Change in household monthly income	Defined as a decrease in the family monthly income range by more than 200 USD between the baseline (T0) and the follow-up (T1). Participants were categorized as having decreased income vs stable or increased income.
Change in income type	Defined as the transition from reliance on a stable income source at baseline (T0) to an unstable or unfixed income source as assistance, transfers, debts, donations, or loans at follow-up (T1).
Change in insurance access	Defined as a transition from insured at baseline (T0) to uninsured at follow-up (T1). The outcome variable was categorized as loss of insurance coverage versus no change in coverage (reference category).
Change in insurance coverage	Defined as the transition in a patient’s insurance coverage between baseline (T0) and follow-up (T1), based on reported categories (hospital fees and treatment, hospital fees only, treatment only, no coverage benefits, uninsured). The variable captures whether the same level of coverage was maintained or reduced over time. A reduction is defined as moving from any insured category at T0 to a lower level of coverage at T1.
Change in payment type	Defined as the change in a patient’s healthcare payment composition between T0 and T1. It captures the transition from the baseline healthcare payment arrangement to a less favorable payment arrangement at follow-up, including increased reliance on out-of-pocket payments, loss of assistance, or other changes indicating reduced financial protection.
Conflict-related change in household setting	Participants were categorized as “unaffected” versus those reporting any Lebanese 2024 conflict-related major change between the two timepoints (including relocation, renting a new residence, or moving in with family or others).
Outcome variables
ECOG performance decline	Defined as a worsening in the patient’s ECOG performance status score between baseline (T0) and follow-up (T1), indicated by an increase in ECOG grade over time.
NCCN compliance decline	Defined as a transition from NCCN-compliant care at baseline (T0) to noncompliant care at follow-up (T1).
Deterioration in treatment receipt	Defined as a decline in treatment receipt between baseline (T0) and follow-up (T1). Participants were classified as having a deterioration in treatment receipt if they reported fully receiving their prescribed treatment at T0 but reported either an incomplete treatment regimen or a reduced treatment dose at T1.

↓ Table 1. Definition of T0 and T1 Changes

Variables

Definition

ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network.

Socioeconomic factors

Change in occupational status

Defined as a deterioration in occupational status between baseline (T0) and follow-up (T1). Participants were categorized as having occupational loss if they transitioned from employment at T0 to unemployment at T1.

Change in household monthly income

Defined as a decrease in the family monthly income range by more than 200 USD between the baseline (T0) and the follow-up (T1). Participants were categorized as having decreased income vs stable or increased income.

Change in income type

Defined as the transition from reliance on a stable income source at baseline (T0) to an unstable or unfixed income source as assistance, transfers, debts, donations, or loans at follow-up (T1).

Change in insurance access

Defined as a transition from insured at baseline (T0) to uninsured at follow-up (T1). The outcome variable was categorized as loss of insurance coverage versus no change in coverage (reference category).

Change in insurance coverage

Defined as the transition in a patient’s insurance coverage between baseline (T0) and follow-up (T1), based on reported categories (hospital fees and treatment, hospital fees only, treatment only, no coverage benefits, uninsured). The variable captures whether the same level of coverage was maintained or reduced over time. A reduction is defined as moving from any insured category at T0 to a lower level of coverage at T1.

Change in payment type

Defined as the change in a patient’s healthcare payment composition between T0 and T1. It captures the transition from the baseline healthcare payment arrangement to a less favorable payment arrangement at follow-up, including increased reliance on out-of-pocket payments, loss of assistance, or other changes indicating reduced financial protection.

Conflict-related change in household setting

Participants were categorized as “unaffected” versus those reporting any Lebanese 2024 conflict-related major change between the two timepoints (including relocation, renting a new residence, or moving in with family or others).

Outcome variables

ECOG performance decline

Defined as a worsening in the patient’s ECOG performance status score between baseline (T0) and follow-up (T1), indicated by an increase in ECOG grade over time.

NCCN compliance decline

Defined as a transition from NCCN-compliant care at baseline (T0) to noncompliant care at follow-up (T1).

Deterioration in treatment receipt

Defined as a decline in treatment receipt between baseline (T0) and follow-up (T1). Participants were classified as having a deterioration in treatment receipt if they reported fully receiving their prescribed treatment at T0 but reported either an incomplete treatment regimen or a reduced treatment dose at T1.

↓ **Table 2.** Baseline Sample Characteristics of the Study Participants (n = 244)
Variables	N	%
Gender
Female	144	59.02
Male	100	40.98
Age group (years)
18–29	9	3.69
30–44	24	9.84
45–59	64	26.23
60–74	113	46.31
75–90	34	13.93
Educational attainment
Illiterate	12	4.92
Primary education	33	13.52
Secondary education	52	21.31
High school education	46	18.85
Higher education	101	41.39
Hospital type
Governmental	23	9.43
Private	221	90.57
Type of admission
Inpatient	51	20.90
Outpatient	193	79.09

↓ Table 2. Baseline Sample Characteristics of the Study Participants (n = 244)

Variables

Gender

Female

144

59.02

Male

100

40.98

Age group (years)

18–29

3.69

30–44

9.84

45–59

26.23

60–74

113

46.31

75–90

13.93

Educational attainment

Illiterate

4.92

Primary education

13.52

Secondary education

21.31

High school education

18.85

Higher education

101

41.39

Hospital type

Governmental

9.43

Private

221

90.57

Type of admission

Inpatient

20.90

Outpatient

193

79.09

↓ **Table 3.** Changes in Social and Clinical Indicators From Baseline (T0) to Follow-Up (T1)
Clinical parameter	T0, n (%)	T1, n (%)	Change variable, n (%)
^aParticipants may report several payment methods; hence percentages do not sum to 100. ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network.
Socio-economic factors
Mean delta dependent children number, mean (SD)	0.59 (1.05)	1.54 (0.88)	0.95 (2.3)
Mean elderly number, mean (SD)	1.78 (0.8)	1.78 (0.8)	No change
Occupational status
Employed	72 (29.5)	65 (26.6)
Retired	29 (11.9)	20 (8.2)
Student	5 (2.0)	5 (2.0)
Unemployed	138 (56.6)	154 (63.1)
Change in occupational status
Remained the same			209 (85.7)
Lost job			35 (14.3)
Household monthly income
< $200	10 (4.1)	11 (4.5)
$200–$500	78 (32.0)	102 (41.8)
$500–$700	53 (21.7)	48 (19.7)
$700–$1,000	36 (14.8)	37 (15.2)
$1,000–$1,500	32 (13.1)	38 (15.6)
> $1,500	35 (14.3)	8 (3.3)
Change in household monthly income
Stable or increased			148 (60.7)
Decrease in income			96 (39.3)
Type of income
Fixed	171 (70.1)	148 (60.7)
Unfixed	73 (29.9)	96 (39.3)
Change in income type
No change			192 (78.7)
Lost fixed income			52 (21.3)
Medical insurance
No	105 (43.0)	101 (41.4)
Yes	139 (57.0)	143 (58.6)
Change in insurance access
No change			229 (93.8)
Lost medical insurance			15 (6.1)
Insurance coverage
Hospital fees and treatment	72 (29.5)	86 (35.3)
Hospital fees only	22 (9.0)	8 (3.3)
Treatment only	4 (1.6)	2 (0.8)
No coverage or uninsured	146 (59.9)	148 (60.7)
Change in insurance coverage
Same coverage			228 (93.4)
Lower level of coverage			16 (6.6)
Payment type^a
Insurance	147 (60.2)	179 (73.4)
Assistance	89 (36.5)	58 (23.8)
Cash	159 (65.2)	163 (66.8)
Change in payment type
No major difference			196 (80.3)
Lost cash or assistance			48 (19.7)
Conflict-related change in household setting
Unaffected			177 (72.5)
Affected			67 (27.5)
Outcome variables
ECOG status
No decline			163 (66.8)
Decline			81 (33.2)
NCCN compliance
Non-compliance decrease			194 (79.5)
Non-compliance increase			50 (20.5)
Overall treatment
No decline			142 (58.2)
Increase in reduced doses/incomplete regimen			102 (41.8)

↓ Table 3. Changes in Social and Clinical Indicators From Baseline (T0) to Follow-Up (T1)

Clinical parameter

T0, n (%)

T1, n (%)

Change variable, n (%)

^aParticipants may report several payment methods; hence percentages do not sum to 100. ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network.

Socio-economic factors

Mean delta dependent children number, mean (SD)

0.59 (1.05)

1.54 (0.88)

0.95 (2.3)

Mean elderly number, mean (SD)

1.78 (0.8)

No change

Occupational status

Employed

72 (29.5)

65 (26.6)

Retired

29 (11.9)

20 (8.2)

Student

5 (2.0)

Unemployed

138 (56.6)

154 (63.1)

Change in occupational status

Remained the same

209 (85.7)

Lost job

35 (14.3)

Household monthly income

< $200

10 (4.1)

11 (4.5)

$200–$500

78 (32.0)

102 (41.8)

$500–$700

53 (21.7)

48 (19.7)

$700–$1,000

36 (14.8)

37 (15.2)

$1,000–$1,500

32 (13.1)

38 (15.6)

> $1,500

35 (14.3)

8 (3.3)

Change in household monthly income

Stable or increased

148 (60.7)

Decrease in income

96 (39.3)

Type of income

Fixed

171 (70.1)

148 (60.7)

Unfixed

73 (29.9)

96 (39.3)

Change in income type

No change

192 (78.7)

Lost fixed income

52 (21.3)

Medical insurance

105 (43.0)

101 (41.4)

Yes

139 (57.0)

143 (58.6)

Change in insurance access

No change

229 (93.8)

Lost medical insurance

15 (6.1)

Insurance coverage

Hospital fees and treatment

72 (29.5)

86 (35.3)

Hospital fees only

22 (9.0)

8 (3.3)

Treatment only

4 (1.6)

2 (0.8)

No coverage or uninsured

146 (59.9)

148 (60.7)

Change in insurance coverage

Same coverage

228 (93.4)

Lower level of coverage

16 (6.6)

Payment type^a

Insurance

147 (60.2)

179 (73.4)

Assistance

89 (36.5)

58 (23.8)

Cash

159 (65.2)

163 (66.8)

Change in payment type

No major difference

196 (80.3)

Lost cash or assistance

48 (19.7)

Conflict-related change in household setting

Unaffected

177 (72.5)

Affected

67 (27.5)

Outcome variables

ECOG status

No decline

163 (66.8)

Decline

81 (33.2)

NCCN compliance

Non-compliance decrease

194 (79.5)

Non-compliance increase

50 (20.5)

Overall treatment

No decline

142 (58.2)

Increase in reduced doses/incomplete regimen

102 (41.8)

↓ **Table 4.** Bivariate Associations Between Sociodemographic and Systemic Characteristics With Main Study Outcomes
Variables	ECOG grade	NCCN compliance	Overall treatment receipt
*P values are significant. ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network.
Age group (years)			0.001*			0.504			0.344
18–29	9 (5.5%)	0 (0%)		6 (3.1%)	3 (6.0%)		4 (2.8%)	5 (4.9%)
30–44	22 (13.5%	2 (2.5%)		20 (10.3%)	4 (8.0%)		17 (12.0%)	7 (6.9%)
45–59	51 (31.3%	13 (16.0%)		51 (26.3%)	13 (26.0%)		36 (25.3%)	28 (27.4%)
60–74	59 (36.2%)	54 (66.7%)		93 (47.9%)	20 (40.0%)		69 (48.6%)	44 (43.1%)
75–90	22 (13.5%)	12 (14.8%)		24 (12.4%)	10 (20.0%)		16 (11.3%)	18 (17.6%)
Gender			0.438			0.258			0.268
Male	99 (60.7%)	45 (55.6%)		118 (60.8%)	26 (52.0%)		88 (62.0%)	56 (54.9%)
Female	64 (39.3%)	36 (44.4%)		76 (39.2%)	24 (48.0%)		54 (38.0%)	46 (45.1%)
Educational level			0.611			0.676			0.316
High school	28 (17.2%)	18 (22.2%)		81 (41.7%)	20 (40.0%)		29 (20.4%)	17 (16.7%)
University	71 (43.6%)	30 (37.0%)		39 (20.1%)	7 (14.0%)		56 (39.4%)	45 (44.1%)
Secondary	37 (22.7%)	15 (18.5%)		41 (21.1%)	11 (22.0%)		35 (24.6%)	17 (16.7%)
Primary	20 (12.3%)	13 (16.0%)		25 (12.9%)	8 (16.0%)		15 (10.6%)	18 (17.6%)
Illiterate	7 (4.3%)	5 (6.2%)		8 (4.1%)	4 (8.0%)		7 (4.9%)	5 (4.9%)
Center			0.085			< 0.001*			0.534
A	42 (25.8%)	12 (14.8%)		46 (23.7%)	8 (16.0%)		34 (23.9%)	20 (19.6%)
B	33 (20.2%)	14 (17.3%)		33 (17.0%)	14 (28.0%)		27 (19.0%)	20 (19.6%)
C	12 (7.4%)	4 (4.9%)		11 (5.7%)	5 (10.0%)		7 (4.9%)	9 (8.8%)
D	11 (6.7%)	12 (14.8%)		11 (5.7%)	12 (24.0%)		11 (7.7%)	12 (11.8%)
E	65 (39.9%)	39 (48.1%)		93 (47.9%)	11 (22.0%)		63 (44.4%)	41 (40.2%)

↓ Table 4. Bivariate Associations Between Sociodemographic and Systemic Characteristics With Main Study Outcomes

Variables

ECOG grade

NCCN compliance

Overall treatment receipt

No decline, N (%)

Decline, N (%)

Sig.

No decline, N (%)

Decline, N (%)

Sig.

No decline, N (%)

Decline, N (%)

Sig.

*P values are significant. ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network.

Age group (years)

0.001*

0.504

0.344

18–29

9 (5.5%)

0 (0%)

6 (3.1%)

3 (6.0%)

4 (2.8%)

5 (4.9%)

30–44

22 (13.5%

2 (2.5%)

20 (10.3%)

4 (8.0%)

17 (12.0%)

7 (6.9%)

45–59

51 (31.3%

13 (16.0%)

51 (26.3%)

13 (26.0%)

36 (25.3%)

28 (27.4%)

60–74

59 (36.2%)

54 (66.7%)

93 (47.9%)

20 (40.0%)

69 (48.6%)

44 (43.1%)

75–90

22 (13.5%)

12 (14.8%)

24 (12.4%)

10 (20.0%)

16 (11.3%)

18 (17.6%)

Gender

0.438

0.258

0.268

Male

99 (60.7%)

45 (55.6%)

118 (60.8%)

26 (52.0%)

88 (62.0%)

56 (54.9%)

Female

64 (39.3%)

36 (44.4%)

76 (39.2%)

24 (48.0%)

54 (38.0%)

46 (45.1%)

Educational level

0.611

0.676

0.316

High school

28 (17.2%)

18 (22.2%)

81 (41.7%)

20 (40.0%)

29 (20.4%)

17 (16.7%)

University

71 (43.6%)

30 (37.0%)

39 (20.1%)

7 (14.0%)

56 (39.4%)

45 (44.1%)

Secondary

37 (22.7%)

15 (18.5%)

41 (21.1%)

11 (22.0%)

35 (24.6%)

17 (16.7%)

Primary

20 (12.3%)

13 (16.0%)

25 (12.9%)

8 (16.0%)

15 (10.6%)

18 (17.6%)

Illiterate

7 (4.3%)

5 (6.2%)

8 (4.1%)

4 (8.0%)

7 (4.9%)

5 (4.9%)

Center

0.085

< 0.001*

0.534

42 (25.8%)

12 (14.8%)

46 (23.7%)

8 (16.0%)

34 (23.9%)

20 (19.6%)

33 (20.2%)

14 (17.3%)

33 (17.0%)

14 (28.0%)

27 (19.0%)

20 (19.6%)

12 (7.4%)

4 (4.9%)

11 (5.7%)

5 (10.0%)

7 (4.9%)

9 (8.8%)

11 (6.7%)

12 (14.8%)

11 (5.7%)

12 (24.0%)

11 (7.7%)

12 (11.8%)

65 (39.9%)

39 (48.1%)

93 (47.9%)

11 (22.0%)

63 (44.4%)

41 (40.2%)

↓ **Table 5.** Unadjusted and Adjusted Logistic Regression Analyses of Factors Associated With ECOG Decline, NCCN Compliance Decline, and Deterioration in Treatment Receipt
Factors	Decline in ECOG status (Yes vs. No -ref-)	Decline in NCCN compliance (Yes vs. No -ref-)	Decline in overall treatment (Yes vs. No -ref-)
^aAdjusted for possible confounders: age, gender. ^bAdjusted age, gender, and center. *P values are significant. 1 is ref. cat. AOR: adjusted odds ratio; CI: confidence interval; ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network; OR: odds ratio.
Mean change in number of children	0.53 (0.3)	0.9 (0.80–1.02)			−0.52 (0.37)				0.95 (0.1)	1.07 (0.96–1.19)	1.1 (0.98–1.23)	0.103
Mean change in number of elderly	0.78 (0.05)	1.75 (1.25–2.45)	1.66 (1.16–2.37)	0.005*	−0.07 (0.12)				−0.08 (0.1)	1.14 (0.83–1.57)	1.22 (0.87–1.70)	0.235
Change in occupational status
Remained same	64 (79.0)	1	1	0.010*	47 (94.0)	1	1	0.117	88 (86.3)	1	1	0.94
Lost job	17 (21.0)	2.13 (1.03–4.42)	2.78 (1.27–6.07)		3 (6.0)	0.32 (0.09–1.10)	0.38 (0.12–1.27)		14 (13.8)	0.91 (0.44–1.90)	0.97 (0.44–2.09)
Change in household monthly income
Stable or increased	50 (61.7)	1							63 (61.7)	1	1	0.792
Decrease in income	31 (38.3)	0.93 (0.54–1.62)							39 (38.2)	0.92 (0.55–1.56)	0.92 (0.53–1.57)
Change in income source
No change	67 (82.3)	1			39 (78.0)	1	1	0.869	81 (79.4)	1	1	0.5
Lost fixed income	14 (17.3)	0.69 (0.35–1.36)			11 (22.0)	1.05 (0.50–2.23)	0.93 (0.42–2.15)		21 (20.6)	0.93 (0.50–1.73)	0.79 (0.41–1.54)
Change in insurance access
No change	77 (95.1)	1			46 (92.0)				95 (93.1)	1	1	0.034*
Lost medical insurance	4 (5.0)	2.02 (1.29–32.8)			4 (8.0)				7 (6.9)	1.23 (0.43–3.51)	2.39 (1.07–5.34)
Change in insurance coverage
Same coverage	77 (97.5)	1			47 (94.0)	1	1	0.548	97 (95.1)	1	1	0.122
Lower level of coverage	2 (2.5)	0.26 (0.12–32.8)			3 (6.0)	0.89 (0.24–3.25)	2.28 (0.51–10.24)		5 (4.9)	1.62 (0.54–4.84)	3.27 (0.72–14.72)
Change in payment type
No major difference	64 (79.0)	1	1	0.238	41 (82.0)	1	1	0.814	80 (78.4)	1	1	0.027*
Lost cash or assistance	17 (21.0)	1.13 (0.58–2.19)	1.66 (0.72–3.85)		9 (18.0)	0.87 (0.39–1.95)	1.12 (0.44–2.85)		22 (21.6)	1.23 (0.65–2.32)	1.30 (1.03–1.64)
2024 Conflict-related change in household setting
Unaffected	56 (69.1)	1	1	0.067					73 (71.6)	1	1	0.451
Affected	25 (30.9)	1.29 (0.71–2.31)	2.04 (0.95-4.37)						29 (28.4)	1.08 (0.61–1.91)	0.95 (0.65–1.78)

↓ Table 5. Unadjusted and Adjusted Logistic Regression Analyses of Factors Associated With ECOG Decline, NCCN Compliance Decline, and Deterioration in Treatment Receipt

Factors

Decline in ECOG status (Yes vs. No -ref-)

Decline in NCCN compliance (Yes vs. No -ref-)

Decline in overall treatment (Yes vs. No -ref-)

Decline, N (%)

Univariate, OR (95% CI)

Multivariate, AOR^a (95% CI)

Sig.

Decline, N (%)

Univariate, OR (95% CI)

Multivariate, AOR^b (95% CI)

Sig.

Decline, N (%)

Univariate, OR (95% CI)

Multivariate, AOR (95% CI)

Sig.

^aAdjusted for possible confounders: age, gender. ^bAdjusted age, gender, and center. *P values are significant. 1 is ref. cat. AOR: adjusted odds ratio; CI: confidence interval; ECOG: Eastern Cooperative Oncology Group; NCCN: National Comprehensive Cancer Network; OR: odds ratio.

Mean change in number of children

0.53 (0.3)

0.9 (0.80–1.02)

−0.52 (0.37)

0.95 (0.1)

1.07 (0.96–1.19)

1.1 (0.98–1.23)

0.103

Mean change in number of elderly

0.78 (0.05)

1.75 (1.25–2.45)

1.66 (1.16–2.37)

0.005*

−0.07 (0.12)

−0.08 (0.1)

1.14 (0.83–1.57)

1.22 (0.87–1.70)

0.235

Change in occupational status

Remained same

64 (79.0)

0.010*

47 (94.0)

0.117

88 (86.3)

0.94

Lost job

17 (21.0)

2.13 (1.03–4.42)

2.78 (1.27–6.07)

3 (6.0)

0.32 (0.09–1.10)

0.38 (0.12–1.27)

14 (13.8)

0.91 (0.44–1.90)

0.97 (0.44–2.09)

Change in household monthly income

Stable or increased

50 (61.7)

63 (61.7)

0.792

Decrease in income

31 (38.3)

0.93 (0.54–1.62)

39 (38.2)

0.92 (0.55–1.56)

0.92 (0.53–1.57)

Change in income source

No change

67 (82.3)

39 (78.0)

0.869

81 (79.4)

0.5

Lost fixed income

14 (17.3)

0.69 (0.35–1.36)

11 (22.0)

1.05 (0.50–2.23)

0.93 (0.42–2.15)

21 (20.6)

0.93 (0.50–1.73)

0.79 (0.41–1.54)

Change in insurance access

No change

77 (95.1)

46 (92.0)

95 (93.1)

0.034*

Lost medical insurance

4 (5.0)

2.02 (1.29–32.8)

4 (8.0)

7 (6.9)

1.23 (0.43–3.51)

2.39 (1.07–5.34)

Change in insurance coverage

Same coverage

77 (97.5)

47 (94.0)

0.548

97 (95.1)

0.122

Lower level of coverage

2 (2.5)

0.26 (0.12–32.8)

3 (6.0)

0.89 (0.24–3.25)

2.28 (0.51–10.24)

5 (4.9)

1.62 (0.54–4.84)

3.27 (0.72–14.72)

Change in payment type

No major difference

64 (79.0)

0.238

41 (82.0)

0.814

80 (78.4)

0.027*

Lost cash or assistance

17 (21.0)

1.13 (0.58–2.19)

1.66 (0.72–3.85)

9 (18.0)

0.87 (0.39–1.95)

1.12 (0.44–2.85)

22 (21.6)

1.23 (0.65–2.32)

1.30 (1.03–1.64)

2024 Conflict-related change in household setting

Unaffected

56 (69.1)

0.067

73 (71.6)

0.451

Affected

25 (30.9)

1.29 (0.71–2.31)

2.04 (0.95-4.37)

29 (28.4)

1.08 (0.61–1.91)

0.95 (0.65–1.78)