World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website https://wjon.elmerpub.com

Original Article

Volume 17, Number 1, February 2026, pages 95-105

A Comparison of Five-Year Survival Rates Between Thermal Ablation and Hepatic Resection for Colorectal Cancer Metastasis to the Liver: A Systematic Review and Meta-Analysis

Figures

Figure 1.
Figure 1. PRISMA chart.
Figure 2.
Figure 2. Five-year overall survival.
Figure 3.
Figure 3. Tumor recurrence.
Figure 4.
Figure 4. Disease-free survival.
Figure 5.
Figure 5. Complication rate.
Figure 6.
Figure 6. Meta-regression bubble plot.

Tables

Table 1. Study and Participant Characteristics
 
AuthorYearDesignLocationSample sizeAge (mean)Males/femalesTumor size (mean, cm)Follow-up (mean, months)
Vogl et al [9]2014RetrospectiveGermany59461.2406:1883.422.5
Chiappa et al [10]2016RetrospectiveItaly36059168:1922.790.3
Dijkstra et al [11]2021ProspectiveAmsterdam13665.1104:3229.1
Puijk et al [12]2022ProspectiveAmsterdam32965.3222:10716.5
Tinguely et al [13]2022ProspectiveSweden10566.864:411.5348
McEachron et al [14]2020RetrospectiveUSA365221:151.928
Hof et al [15]2016RetrospectiveNetherlands43162.9264:1673.538.6
Huang et al [16]2021RetrospectiveChina18457.4112:7251.3
Wang et al [17]2017RetrospectiveChina9659.574:224.5
Masuda et al [18]2018RetrospectiveUSA and Japan71758.5429:2883
Knott et al [19]2021ProspectiveUSA576035:221.849.3
Valls et al [20]2014ProspectiveSpain5964.141:182.325.3
De Graaff et al [21]2024RetrospectiveNetherlands2,00864.51,271:73776.9
Shady et al [22]2016RetrospectiveUSA16292:7055
Lee et al [23]2022RetrospectiveSouth Korea9260.263:291.433

 

Table 2. Characteristics of Each Group
 
AuthorYearAblation/resection
Sample sizeMales/femalesAge (mean)Hospital length stay (mean, days)
Chiappa et al [10]201680/28037:43/131:14958/609/8
Dijkstra et al [11]2021100/3679:21/25:1166.9/63.31/5
Tinguely et al [13]202252/5333:19/31:2267.5/661/7
Huang et al [16]202198/8656:42/56:3058.8/55.93.5/7
Masuda et al [18]2018116/60174:42/355:24558.5/58.4
De Graaff et al [21]20241,005/1,003644:361/627:37664/65

 

Table 3. Summary of Pooled Analysis
 
OutcomesEffect sizeCIHeterogeneity I2P value
CI: confidence interval; OR: odds ratio; RR: relative risk.
Overall survivalRR: 0.840.54 - 1.3094%0.35
Tumor recurrenceOR: 1.661.06 - 2.6210%0.03
Disease-free survivalRR: 1.000.32 - 3.1389%0.99
ComplicationsOR: 0.340.09 - 1.2184%0.08