World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website https://wjon.elmerpub.com

Letter to the Editor

Volume 16, Number 2, April 2025, pages 235-238


CD19 Expression in B-Cell Lymphomas and Clinical Considerations in the Evolving Landscape of CD19-Targeted Therapy

Table

↓  Table 1. CD19 Expression Analysis at Diagnosis and Relapse
 
Number (%)
Patients with B-cell non-Hodgkin lymphoma 288
  Diffuse large B-cell lymphoma 143 (49.7%)
  Follicular lymphoma 38 (13.2%)
  Marginal zone lymphoma 22 (7.6%)
  High-grade B-cell lymphoma 19 (6.6%)
  Mantle cell lymphoma 12 (4.2%)
  Other 54 (18.7%)
Patients with diagnostic biopsy results available 228 (79.2%)
CD19 expression on diagnostic biopsy 92
  CD19 positive 88 (95.6%)
  CD19 dim 1 (1.1%)
  CD19 negative 3 (3.3%)
Patients with relapsed or refractory disease 109 (37.8%)
Number of relapses across all patients 155
Relapses with biopsy performed 75
  CD19 expression on relapse biopsy 35
  CD19 positive 34 (97.1%)
  CD19 dim 0 (0%)
  CD19 negative 1 (2.9%)